Week 7 kicks off with Pittsburgh at Cincinnati on Thursday Night Football, followed by London’s Rams vs. Jaguars and the Colts at Chargers. Bills and Ravens are on bye. The odds table shows a mix of sizable favorites and close picks, including Steelers -5.5 at CIN, Rams -3.5 over JAX, and Chiefs as heavy favorites. Several matchups churn high-scoring potential while others hinge on defensive play and game script. Rosters should heed byes and travel effects as the slate unfolds.

Key Week 7 themes: spread-driven fantasy value in shootouts (TB vs DET, PHI vs MIN, ATL vs SF), streaming defenses in favorable matchups, and careful lineup construction around late-window games (IND-LAC, WSH-DAL). Monitor injury updates and weather, especially for London and prime time games, to capitalize on mismatches and avoid landmines.

Za'Darius Smith announced his retirement after Week 6, leaving the Eagles light at edge rusher. In five games with Philadelphia, he tallied 10 tackles, 1.5 sacks, and 10 pressures on 131 snaps, after a 9-sack, 38-pressure season with Browns/Lions. A three-time Pro Bowler, twice with Green Bay and once with Minnesota, his exit alters the Eagles’ pass‑rush plans and raises questions for late-season fantasy lineups.